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Updated: May 9, 2026

Isolation of Adipose Tissue Immune Cells
Published on: May 22, 2013
Adipose stem cells drive T cell infiltration in obesity
Aneta Balcerczyk1, Assia Eljaafari2, Luciano Pirola3
1Department of Oncobiology and Epigenetics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, Lodz 90-236, Poland.
None:
Obesity is often associated with adipose tissue (AT) inflammation and immune cell infiltration. Writing recently in Cell Reports, Liao et al. investigated the mechanisms of T cell infiltration of AT using single cell (sc)RNA-sequencing (RNA-seq), transplantation studies, in vitro co-cultures, and knock-out mice. They highlighted the crucial role of C-C motif chemokine ligand 5 (CCL5)-secreting adipose stem cells (ASCs), offering insights for potential therapies.

