Epidural Block in a Patient With Melkersson-Rosenthal Syndrome: A Case Report

Area of Science:

• Anesthesiology
• Neurology
• Genetics

Background:

• Melkersson-Rosenthal syndrome (MRS) is a rare neurological disorder characterized by facial nerve palsy, swelling, and fissured tongue.
• MRS can present with sudden airway complications, posing significant risks during medical procedures.
• Limited data exists on anesthetic management for patients with MRS, particularly during labor.

Observation:

• A pregnant patient with Melkersson-Rosenthal syndrome required labor analgesia.
• The patient had a history of potential airway complications associated with MRS.
• An epidural block was considered as a potential anesthetic option.

Findings:

• The first application of an epidural block for labor analgesia in a patient with Melkersson-Rosenthal syndrome was successfully performed.
• A specifically tailored epidural protocol effectively managed MRS symptoms and prevented exacerbation.
• The patient achieved a complication-free vaginal delivery under regional anesthesia.

Implications:

• This case report provides valuable insights into the safe use of regional anesthesia in patients with Melkersson-Rosenthal syndrome.
• It highlights the importance of individualized anesthetic planning for rare conditions with potential airway risks.
• The findings contribute to the limited literature on perioperative considerations for general or regional anesthesia in MRS patients.