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Updated: Jun 22, 2025
Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts
Published on: June 13, 2019
Undifferentiated Pleomorphic Sarcoma of the Descending Colon: An Infrequent Occurrence
Pir Abdul Ahad Aziz Qureshi1,2, Shah Zeb1, Thordur Tryggvason3
1Department of Radiology, Landspítali - The National University Hospital of Iceland, Reykjavík, ISL.
Abstract:
Undifferentiated pleomorphic sarcoma (UPS), formerly known as malignant fibrous histiocytoma (MFH), constitutes a significant subset of soft-tissue sarcomas. Despite its rarity, UPS poses substantial clinical challenges due to its aggressive behavior and propensity for distant metastasis. Here, we report a rare case of high-grade UPS located in the colon, a site exceptionally uncommon for this malignancy, in a 49-year-old woman. The case also underscores the importance of considering UPS in the differential diagnosis of colonic neoplasms. Understanding the clinical and pathological features of UPS in unusual locations like the large intestine is crucial for timely diagnosis and appropriate management strategies.
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