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Updated: Jun 22, 2025
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Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring
Published on: May 17, 2024
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[Reproductive Health-Oriented Development in Assisted Reproductive Technologies].
Peiran Hu1, Jiexue Pan1, Xinmei Liu1
1（ 200030） Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai 200030, China.
Summary
Assisted reproductive technologies (ARTs) offer hope for infertility but raise safety concerns. This review examines common ARTs, advancements, and their impact on patient and offspring reproductive health.
Area of Science:
- Reproductive Medicine
- Developmental Biology
- Genetics
Background:
- Global fertility rates are declining, increasing reliance on assisted reproductive technologies (ARTs).
- Concerns exist regarding potential adverse effects of ARTs on reproductive health.
- ARTs encompass crucial early developmental stages: gamete maturation, fertilization, and embryo development.
Purpose of the Study:
- To discuss common ART procedures and recent advancements.
- To reevaluate the role of ARTs in promoting reproductive health.
- To explore the impact of ARTs on offspring reproductive health.
Main Methods:
- Review of common ARTs: in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), biphasic in vitro maturation (biphasic IVM), frozen embryo transfer (FET).
- Discussion of genetic testing techniques: preimplantation genetic testing (PGT) and non-invasive PGT (niPGT).
- Analysis of ARTs within the context of overall reproductive health and well-being.
Main Results:
- ARTs are evolving with cutting-edge advancements to improve efficacy and safety.
- The study provides a comprehensive overview of current ART practices.
- Potential impacts on both patients and offspring are considered.
Conclusions:
- Continuous improvement of ARTs is vital for enhancing reproductive health outcomes.
- Prioritizing the reproductive well-being of patients and offspring is essential.
- ART advancements contribute significantly to the field of human reproduction.
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