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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
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Surgical therapy in advanced sinonasal carcinomas - retrospective study
Lumir Hrabalek1, Vlastimil Novak1, Jiri Hoza2
1Department of Neurosurgery, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic.
Summary
This study evaluated a combined surgical approach for advanced sinonasal tumors. The combined frontal transbasal and endoscopic endonasal approach achieved complete tumor resection in 80% of patients, improving outcomes.
Area of Science:
- Otolaryngology
- Neurosurgery
- Surgical Oncology
Background:
- Sinonasal tumors are rare, heterogeneous malignant neoplasms.
- Surgical resection is the primary treatment modality.
- Advanced stages present significant therapeutic challenges.
Purpose of the Study:
- To report surgical outcomes for advanced sinonasal tumors.
- To evaluate a combined surgical approach.
- To assess tumor resection radicality, recurrence, complications, and survival.
Main Methods:
- Retrospective analysis of patients with advanced sinonasal tumors undergoing surgery.
- Utilized a combined frontal transbasal and endoscopic endonasal surgical approach.
- Evaluated tumor histology, resection completeness (R0), recurrence rates, complications, adjuvant therapy, and overall survival.
Main Results:
- Ten patients (7 male, 3 female) were included.
- Complete resection (R0) achieved in 80% of cases; subtotal resection in 20%.
- Mean overall survival was 28.7 months (95% CI 15.9-41.6).
Conclusions:
- The combined approach facilitates complete resection of advanced sinonasal tumors.
- This technique aids in anterior skull base reconstruction.
- It potentially reduces the extent of surgical intervention.
