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Updated: Jun 22, 2025
Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes
Published on: December 16, 2019
Platinum-Catalyzed Hydrative Dimerization of Alkynylsilanes to α,β-Unsaturated Ketones
Kasumi Kikuchi-Igarashi1, Yuki Tahara1, Haruna Hirano1
1Department of Applied Chemistry, Graduate School of Science and Engineering, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan.
Abstract:
A unique type of platinum catalysis that is valuable for the synthesis of α,β-unsaturated ketones is described. In the presence of PtCl2, (2-arylethynyl)trimethylsilanes reacted with H2O at 30 °C to give 1,4-diarylbut-3-en-2-ones in moderate to good yields. (2-Alkylethynyl)trimethylsilanes could be efficiently converted into the corresponding hydrative dimerization products by a modified Pt catalyst system. Mechanistic studies suggest the participation of acylplatinum intermediates in the catalytic cycle.
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