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Human milk oligosaccharide 2'-fucosyllactose guards norovirus histo-blood group antigen co-factor binding site

Penny A Rudd1, Gargi Kher2, Jeremy R H Tame3

  • 1Institute for Glycomics, Griffith University, Gold Coast Campus, Gold Coast, Queensland, Australia.

Journal of Virology
|July 2, 2024
PubMed
Abstract

No abstract available in PubMed .

Keywords:
X-ray crystallographyantiviral agentsnoroviruses

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Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
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