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Martine Siw Nielsen1,2, Maria Bisgaard Borup1,3, Jens Kjeldsen4

  • 1Syddansk Center for Interstitielle Lungesygdomme (SCILS), Lungemedicinsk Afdeling, Odense Universitetshospital.

Ugeskrift for Laeger
|July 2, 2024
PubMed
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A woman with chronic bowel-associated dermatosis-arthritis syndrome developed laryngeal edema due to persistent cough. Early intervention is crucial for complex cases to prevent severe hospitalizations.

Area of Science:

  • Internal Medicine
  • Pulmonology
  • Otolaryngology

Background:

  • This case report details a rare instance of laryngeal edema in a patient with chronic bowel-associated dermatosis-arthritis syndrome and left main bronchus stenosis.
  • The patient presented with significant respiratory compromise necessitating intubation.

Observation:

  • Laryngeal edema was observed in a 35-year-old female patient with pre-existing complex medical conditions.
  • Persistent cough, delayed treatment, and intubation-related irritation were identified as contributing factors.
  • Diagnostic evaluations excluded inflammatory, autoimmune, and malignant etiologies for the laryngeal edema.

Findings:

  • The primary finding is the occurrence of laryngeal edema causally linked to persistent cough in a patient with significant comorbidities.

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  • This presentation highlights a potential, though rarely documented, complication of severe coughing episodes.
  • The absence of other causative factors underscores the role of mechanical stress from coughing.
  • Implications:

    • This case underscores the need for prompt recognition and management of severe cough in patients with serious underlying conditions.
    • A multidisciplinary approach involving pulmonology, otolaryngology, and critical care is recommended for optimal patient outcomes.
    • Early intervention may prevent severe complications such as airway obstruction and prolonged hospitalization.