Related Experiment Video
Updated: Jun 22, 2025

A Closed-chest Model to Induce Transverse Aortic Constriction in Mice
Published on: April 5, 2018
Accidental compression of the thoracic wall. Mechanical asphyxia rather than trauma is the main culprit
Christos Voucharas1, Angeliki Vouchara1, Fani Tsolaki1
1Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54636, Greece.
Abstract:
We present three cases of traumatic asphyxia after thoracic compression. All victims were Caucasian males aged 22-50 years. One man was crushed by a truck trailer, another was crushed by an overturned vehicle, and the last was crushed by a large heavy stone slab. None of the patients survived the accident. There was no evidence of trauma or only minor trauma from the bones or vital organs of the thoracic cavity and abdomen.
Related Concept Videos
Pneumothorax-I
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pneumothorax-II
Clinical Manifestations:
Flail Chest-I
Flail chest is a severe and potentially life-threatening condition characterized by the fracture of three or more adjacent ribs in multiple places. It is most commonly caused by direct impacts and trauma, such as motor vehicle accidents or injuries from a steering wheel impact. It can also occur due to falls in elderly individuals with osteoporosis, or assaults involving sharp objects.
Pathophysiology
The pathophysiology of flail chest is complex, involving fractures of...
Flail Chest-II
Assessment:
1. Clinical Evaluation:
History:
Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Acute Respiratory Failure-III

