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Clinical-instrumental relationships in post-phlebitic syndrome
Angiology
|January 1, 1985
Summary
Deep vein thrombosis (DVT) impacts venous pressure, with higher pressures observed in femoro-iliac thrombosis compared to calf vein occlusions. Post-thrombotic syndrome venous pressure varies based on location and time since phlebitis onset.
Area of Science:
- Vascular Medicine
- Phlebology
- Cardiovascular Physiology
Background:
- Deep vein thrombosis (DVT) is a significant vascular condition.
- Understanding venous pressure dynamics is crucial for managing DVT and its sequelae.
- Previous research has explored DVT's impact, but detailed pressure analysis over time requires further investigation.
Purpose of the Study:
- To analyze venous pressure in lower limbs affected by deep vein thrombosis.
- To investigate the relationship between thrombosis location (femoro-iliac vs. calf veins) and venous pressure.
- To examine the long-term venous pressure changes in post-thrombotic syndrome and their correlation with aetiopathogenesis.
Main Methods:
- Examination of 981 lower limbs from 829 subjects, with detailed venous pressure measurements.
- Comparison of venous pressures in cases of femoro-iliac thrombosis versus calf vein occlusions.
- Analysis of venous pressure trends over time in post-thrombotic syndrome, considering initial phase and long-term stability.
Main Results:
- Average venous pressure in the tibial posterior vein was 101 mmHg and in the internal saphenous vein was 102 mmHg.
- Venous pressures were slightly higher in femoro-iliac thrombosis (311 limbs) compared to calf vein occlusions (670 limbs).
- Iliac post-thrombotic syndrome showed consistently high venous pressures, while leg post-thrombotic syndrome pressures increased over 2-4 years post-phlebitis, stabilizing at lower levels than iliac syndrome. Saphenous vein pressure exceeded deep pressures in iliac post-thrombotic syndrome.
Conclusions:
- Venous pressure is elevated in DVT, with distinct patterns based on thrombosis location and post-thrombotic syndrome development.
- Long-term venous pressure monitoring reveals different trajectories for iliac versus leg post-thrombotic syndromes.
- Altered venous return, particularly in the saphenous system, may contribute to elevated pressures in iliac post-thrombotic syndrome.