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Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Novel Peri-Operative Strategy for Sickle Cell Disease with Tetralogy of Fallot
Naveed Khan1, Vaibhav Dhabe1, Ameya Kaskar2
1Department of Cardiac Anesthesia, NH SRCC Children's Hospital, Mumbai, Maharashtra, India.
Abstract:
Peri-operative management of cyanotic congenital heart disease in a patient of sickle cell disease (SCD) can be challenging. We report a case of Tetralogy of Fallot and homozygous SCD with history of multiple blood transfusions and sickle cell crises who underwent intracardiac repair. Hemoglobin S level was reduced from 75% pre-operative to 21.8% postoperative with a combination of pre-operative blood transfusion, intraoperative exchange transfusion, and normothermic cardiopulmonary bypass (CPB). Pre-operative optimization and safe intraoperative conduct were essential to avoid sickling crises.
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