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Vasoactive-Inotropic Scoring in Cardiac Surgery: Both Concept and Context Matter!

Jaffrey Kalaiselvan1, Rohan Magoon1, Ramesh C Kashav1

  • 1Department of Cardiac Anaesthesia, Atal Bihari Vajpayee Institute of Medical Sciences (ABVIMS) and Dr. Ram Manohar Lohia Hospital, Baba Kharak Singh Marg, New Delhi, India.

Annals of Cardiac Anaesthesia
|July 4, 2024
PubMed
Summary

No abstract available in PubMed .

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Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
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