SACRAL NEUROMODULATION IN TREATING OVERACTIVE BLADDER PATIENTS - FIRST-TIME APPLICATION IN CROATIA
Mirko Bakula1, Dinko Hauptman1, Tvrtko Hudolin1
1Department of Urology, Zagreb University Hospital Center, Zagreb, Croatia.
Acta Clinica Croatica
|July 5, 2024
Summary
Sacral neuromodulation (SNM) offers a safe and effective treatment for overactive bladder and fecal incontinence. This minimally invasive therapy modulates neural pathways, providing relief for refractory symptoms.
Area of Science:
- Neurology
- Urology
- Gastroenterology
Background:
- Sacral neuromodulation (SNM) is an advanced therapy utilizing electrical stimulation of sacral nerve roots.
- It is indicated for overactive bladder (OAB), urinary incontinence, urinary retention, urgency, frequency, and fecal incontinence.
- SNM is also approved for chronic constipation in Europe and Canada.
Purpose of the Study:
- To elucidate the mechanism of action of SNM.
- To highlight its efficacy in treating various lower urinary and bowel dysfunction symptoms.
- To introduce SNM as a novel therapeutic option.
Main Methods:
- Electrical stimulation of sacral nerve roots.
- Modulation of neural pathways in central and peripheral nervous systems.
- Potential inhibition of bladder afferent pathways via pudendal nerve stimulation.
Main Results:
- Over 300,000 patients treated globally over two decades.
- Confirmed efficacy in relieving refractory OAB symptoms.
- Successful management of urinary retention and fecal incontinence.
Conclusions:
- SNM is a safe and efficacious treatment for refractory bladder and bowel dysfunction.
- The precise mechanism of action requires further investigation.
- SNM represents a valuable novel therapeutic option for patients.
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