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Updated: May 10, 2026
18:48
Murine Renal Transplantation Procedure
Published on: July 10, 2009
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MANAGEMENT OF PROSTATE CANCER IN KIDNEY TRANSPLANT RECIPIENTS
Zoran Zimak1, Ivica Mokos1,2, Hrvoje Saić1
1Department of Urology, Zagreb University Hospital Center, Zagreb, Croatia.
Acta Clinica Croatica
|July 5, 2024
Summary
Radical prostatectomy is a safe treatment for localized prostate cancer (PC) in kidney transplant recipients. This approach effectively manages PC without negatively impacting graft function or survival rates.
Area of Science:
- Urology
- Nephrology
- Oncology
Background:
- Kidney transplantation is the primary treatment for end-stage kidney disease.
- Prostate cancer (PC) is a common malignancy in men.
- Managing PC in kidney transplant recipients presents challenges due to immunosuppression and graft location.
Purpose of the Study:
- To analyze the incidence, treatment, and outcomes of prostate cancer in kidney transplant recipients.
- To evaluate the safety and efficacy of radical prostatectomy in this patient population.
Main Methods:
- Retrospective analysis of male kidney transplant recipients diagnosed with PC between 2002 and 2022.
- Review of patient data including incidence, treatment modalities, and follow-up outcomes.
Main Results:
- PC was diagnosed in 1.11% (12/1079) of male kidney transplant recipients.
- Radical prostatectomy was performed in 11 patients; one received radiotherapy.
- Eleven patients maintained stable graft function; one graft nephrectomy occurred unrelated to PC.
Conclusions:
- Radical prostatectomy is a safe and effective treatment for localized PC in kidney transplant recipients.
- Treatment does not compromise graft function or recipient survival.
- Further monitoring and PSMA PET CT indicated for select cases.
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