Ulcerative colitis associated mononeuritis multiplex in 75-year-old patient: Rare case report

Area of Science:

• Gastroenterology
• Neurology
• Rheumatology

Background:

• Inflammatory bowel disease (IBD) encompasses chronic gastrointestinal inflammatory disorders with relapsing-remitting patterns.
• Ulcerative colitis (UC) is a major form of IBD, often presenting with chronic diarrhea and systemic manifestations.
• Mononeuritis multiplex is a rare neurological complication characterized by inflammation of multiple individual peripheral nerves.

Observation:

• A 75-year-old male with a history of hypertension, arthritis, erythema nodosum-like lesions, and chronic diarrhea was hospitalized.
• The patient presented with symptoms suggestive of ulcerative colitis and neurological involvement.
• Diagnostic workup included colonoscopy, electromyography, nerve conduction studies, and echocardiography.

Findings:

• The patient was diagnosed with ulcerative colitis presenting as a rare clinical scenario associated with mononeuritis multiplex.
• Comprehensive diagnostic assessments confirmed the co-occurrence of these conditions.
• The patient's condition showed significant improvement following a specific treatment regimen.

Implications:

• This case highlights the importance of considering neurological complications like mononeuritis multiplex in patients with ulcerative colitis.
• Early diagnosis and appropriate management are crucial for improving patient outcomes in such rare presentations.
• Further research into the pathophysiological links between IBD and neurological disorders is warranted.