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Native Aortic Valve Endocarditis Caused by Scopulariopsis Species: Case Report, Considerations for Management, and
Sabrina Imam1, Christopher J Kaperak1, Ahmed E Hozain2
1Section of Infectious Diseases and Global Health, University of Chicago Medicine, Chicago, Illinois, USA.
Abstract:
We present the first case of native aortic valve endocarditis caused by Scopulariopsis. Intraoperative images and videos from valve replacement surgery illustrate the severity of fungal endocarditis. This case demonstrates the aggressive presentation of left-sided fungal endocarditis, highlights challenges with treating highly resistant fungi, and considers the potential utility of olorofim.
Insights
This study reports the first case of native aortic valve endocarditis caused by Scopulariopsis. It highlights aggressive fungal endocarditis and treatment challenges, suggesting potential use of olorofim.
Area of Science:
- Cardiology
- Infectious Diseases
- Mycology
Background:
- Native aortic valve endocarditis is a severe infection.
- Fungal endocarditis is rare but carries high mortality.
- Scopulariopsis is an emerging cause of invasive fungal infections.
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