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Giant parathyroid lipoadenoma case report: A parathyroid phenomenon
K Griffin1, K McKnight1, B Al-Kendi1
1Department of Surgery, Galway University Hospitals, Republic of Ireland.
International Journal of Surgery Case Reports
|July 6, 2024
Summary
Parathyroid lipoadenomas, rare causes of primary hyperparathyroidism, present diagnostic challenges. This report details the largest known case, emphasizing its importance in differential diagnoses for endocrine surgeons and pathologists.
Area of Science:
- Endocrinology
- Surgical Pathology
Background:
- Parathyroid lipoadenomas are rare neoplasms, infrequently causing primary hyperparathyroidism.
- Fewer than 100 cases have been documented since their initial description in 1958.
Observation:
- A male patient presented with symptomatic primary hyperparathyroidism and a large neck mass.
- Minimally invasive parathyroidectomy with intraoperative parathyroid hormone monitoring was successfully performed.
Findings:
- A giant parathyroid lipoadenoma was excised, confirmed by a significant drop in intraoperative parathyroid hormone levels.
- The lesion's high adipose content complicates imaging localization and can mislead pathologists.
Implications:
- This case expands the literature on parathyroid lipoadenomas, highlighting diagnostic difficulties for surgeons, radiologists, and pathologists.
- Recognizing parathyroid lipoadenoma as a differential diagnosis is crucial for managing primary hyperparathyroidism.
