Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Bacteraemias due to Enterococci in Burns: Incidence and Factors Associated to Mortality].

Annals of burns and fire disasters·2026
Same author

Abstracts Association Tunisienne de Médecine Néonatale (ATMN).

La Tunisie medicale·2026
Same author

[Severe burns in Pregnant Women: Incidence and Factors Associated with Mortality].

Annals of burns and fire disasters·2026
Same author

Epidemiology and Prognosis of Burns in the Elderly: Study of 100 Cases.

Annals of burns and fire disasters·2026
Same author

[Toxic Epidermal Necrolysis: Study of an 81-case Series].

Annals of burns and fire disasters·2026
Same author

Colistin-Associated Acute Kidney Injury in Burn Patients: Incidence, Associated Factors and Prognosis.

Annals of burns and fire disasters·2026

Related Experiment Video

Updated: Jul 16, 2026

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
08:58

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

6.4K

[DISTRIBUTION OF CARBAPENEMASES IN TUNISIAN BURN PATIENTS].

A Mokline, S Zarrouk, I Jemi

    Annals of Burns and Fire Disasters
    |July 8, 2024
    PubMed
    Summary

    Carbapenemase-producing bacteria are spreading in burn units. Identifying carriers is crucial for infection control, with VIM, NDM, and OXA48 enzymes being prevalent in Tunisia.

    Keywords:
    burnscarbapenemsintensive caremapping

    More Related Videos

    Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae
    06:04

    Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae

    Published on: February 24, 2023

    2.4K
    Rapid and Specific Detection of Acinetobacter baumannii Infections Using a Recombinase Polymerase Amplification/Cas12a-based System
    07:59

    Rapid and Specific Detection of Acinetobacter baumannii Infections Using a Recombinase Polymerase Amplification/Cas12a-based System

    Published on: April 25, 2025

    215

    Related Experiment Videos

    Last Updated: Jul 16, 2026

    Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
    08:58

    Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

    Published on: March 3, 2023

    6.4K
    Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae
    06:04

    Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae

    Published on: February 24, 2023

    2.4K
    Rapid and Specific Detection of Acinetobacter baumannii Infections Using a Recombinase Polymerase Amplification/Cas12a-based System
    07:59

    Rapid and Specific Detection of Acinetobacter baumannii Infections Using a Recombinase Polymerase Amplification/Cas12a-based System

    Published on: April 25, 2025

    215

    Area of Science:

    • Medical Microbiology
    • Infectious Diseases
    • Public Health

    Context:

    • Carbapenem resistance is a growing global health threat, particularly in healthcare settings.
    • Burn patients are vulnerable to multidrug-resistant organisms due to compromised skin barriers and prolonged hospital stays.
    • Effective infection control strategies are essential to curb the spread of carbapenemase-producing Enterobacteriaceae (CPE).

    Purpose:

    • To determine the prevalence and distribution of carbapenemase-producing bacteria in burn patients in Tunisia.
    • To identify specific carbapenemase genes (VIM, NDM, OXA-48) and their carriage patterns.
    • To investigate potential risk factors associated with carbapenemase carriage in this patient population.

    Summary:

    • A 9-month study in a Tunisian burn center utilized PCR to screen all admitted patients for carbapenemase carriage within 48 hours.
    • Prevalence of single, double, and triple carbapenemase carriage was observed in 17, 11, and 25 patients, respectively.
    • The most common enzymes detected were Verimo-1 (VIM), New Delhi metallo-beta-lactamase (NDM), and Oxacillinase-48 (OXA-48). Enzyme mapping identified Kairouan and Kasserine as key areas of carriage.

    Impact:

    • Findings highlight the urgent need for enhanced surveillance and infection control measures in Tunisian burn units to combat multidrug-resistant bacteria.
    • Identification of specific carbapenemase types and geographical hotspots aids in targeted interventions.
    • Predictive factors such as prior antibiotic use, mechanical ventilation, and catheterization underscore the importance of optimizing patient management to reduce transmission risk.