Related Experiment Video

Updated: Jun 21, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
07:41

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

Published on: February 20, 2018

8.9K

Relevance of G protein-coupled receptor (GPCR) dynamics for receptor activation, signalling bias and allosteric

Marta Lopez-Balastegui1, Tomasz Maciej Stepniewski1,2, Małgorzata M Kogut-Günthel3

  • 1Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute & Pompeu Fabra University, Barcelona, Spain.

British Journal of Pharmacology
|July 9, 2024
PubMed

Keywords:
Allosteric modulationDrug designGPCR dynamicsMolecular dynamics simulationsSignalling biasTime‐resolved experimental techniques

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