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Curcumin Nanocapsules based on carbon dots for photodynamic sterilization towards Listeria monocytogenes and
Xiaoqin Pan1, Shan Xiao1, Bo Wang1
1School of Life and Health Technology, Dongguan University of Technology, Dongguan 523808, PR China; Dongguan Key Laboratory of Prepared Dishes Innovative Development & Quality Control, Regional Brand Innovation & Development Institute of Dongguan Prepared Dishes, Dongguan 523808, PR China.
Abstract:
Curcumin (Cur) as a natural food additive and photosensitizer has been widely applied on photodynamic sterilization and preservation for food, but the poor aqueous solubility and light stability restrict its extensive application. In this study, we report a Cur nanocapsules (Cur-CDs) made by carbon dots (CDs). Attributing to the hydrogen bonds formed between Cur and CDs, Cur-CDs exhibits excellent Cur aqueous solubility each to 9286.98 ng/mL (enhanced by 246.27 times) and light stability (enhanced by 1.51 times). The photogenerated electron transmission from Cur to CDs in addition resulted in >1.23 and 1.60 times generation of •O2- and •OH, compared to that of bare Cur. Accordingly, 5.73 × 103 CFU L. monocytogenes, and 5.43 × 103 CFU S. aureus were killed by 0.06 mg/mL Cur-CDs within 20 mins of blue light, showing the promising potential in the development and application of safe and environmentally friendly non-thermal sterilization technology based on Cur-CDs.
