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Diabetic Retinopathy

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DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

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Related Experiment Video

Updated: May 4, 2026

A Mouse Model of Retinal Ischemia-Reperfusion Injury Through Elevation of Intraocular Pressure

A Mouse Model of Retinal Ischemia-Reperfusion Injury Through Elevation of Intraocular Pressure

Published on: July 14, 2016

Acute retinal necrosis: A mini review.

Florence Hoogewoud¹, Daniele C Rossi¹, Theodor Stappler¹

¹Hôpital Ophtalmique Jules-Gonin, FAA, Université de Lausanne, Lausanne, Switzerland.

Frontiers in Ophthalmology

|July 10, 2024

Summary

Acute retinal necrosis, a severe eye condition, often leads to vision loss from retinal detachment. Current treatments include IV acyclovir, valacyclovir, and foscarnet, with ongoing research into prophylactic laser and vitrectomy to improve outcomes.

Keywords:

acute retinal necrosis (ARN)acyclovir herpes simplex retinal detachment varicella zoster

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Last Updated: May 4, 2026

A Mouse Model of Retinal Ischemia-Reperfusion Injury Through Elevation of Intraocular Pressure

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Published on: July 14, 2016

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents

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Retinal Pathophysiological Evaluation in a Rat Model

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Published on: May 6, 2022

Area of Science:

Ophthalmology
Infectious Diseases

Background:

Acute retinal necrosis is a rare, severe ocular disease.
Retinal detachment is a common complication, causing vision loss and phthisis bulbi.

Purpose of the Study:

To review current diagnostic and treatment strategies for acute retinal necrosis.
To explore methods for reducing the rate of retinal detachment.

Main Methods:

Review of existing literature on acute retinal necrosis diagnosis and management.
Analysis of treatment options including IV acyclovir, valacyclovir, and intravitreal foscarnet.
Evaluation of prophylactic laser treatment and early vitrectomy for complication reduction.

Main Results:

Intravenous acyclovir is the standard treatment.
High-dose valacyclovir and intravitreal foscarnet are alternative therapies.
Prophylactic laser and early vitrectomy are proposed to decrease retinal detachment rates.

Conclusions:

Acute retinal necrosis requires prompt diagnosis and management.
Treatment strategies aim to prevent vision loss and preserve ocular structures.
Further research may focus on optimizing interventions to minimize complications like retinal detachment.