Chemotherapeutic agents and future fertility

The recent progress in antiblastic therapy has achieved significant successes in the treatment of tumors, obtaining in some cases a complete recovery and very frequently a remission of the disease for a considerable number of years. Therefore the clinician has to deal with the problem of long term toxicity which always accompanies these therapies. This aspect was once considered as a secondary feature in respect to the severity of prognosis quod vitam of the subjects affected with cancer, while now, with a significant increase of survival, it is preeminent that there be the possibility to offer these patients an acceptable quality of life under both physical and social profiles. The reintroduction of patients affected with cancer or treated ones into their social and familiar functions must take into account many factors which are bound to the degree of physical integrity, to psychological conditioning and problems of resumption of working activity. Under a strictly social profile it is fundamental to have knowledge of troubles and disturbances that may involve the reproductive sphere.