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Related Experiment Video

Updated: Jun 21, 2025

Intravital Microscopy of Tumor-associated Vasculature Using Advanced Dorsal Skinfold Window Chambers on Transgenic Fluorescent Mice
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Exploring Extravasation in Cancer Patients.

Tuan D Pham1, Taichiro Tsunoyama2

  • 1Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AD, UK.

Cancers
|July 13, 2024
PubMed
Summary

Extravasation, leakage of IV drugs during cancer treatment, requires better prevention and management. This review highlights new technologies like AI and smart catheters to improve patient safety and outcomes.

Keywords:
cancer treatmentchemotherapyemerging technologiesextravasationprevention and managementradiotherapy

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Area of Science:

  • Oncology
  • Patient Safety
  • Medical Technology

Background:

  • Extravasation, the unintended leakage of intravenous substances, is a significant complication in cancer treatment.
  • It poses challenges during chemotherapy and radiotherapy, impacting patient safety and treatment efficacy.

Purpose of the Study:

  • To comprehensively review extravasation in cancer patients, covering pathophysiology, risk factors, diagnosis, management, and long-term effects.
  • To identify knowledge gaps and propose future research directions for extravasation prevention and management.
  • To highlight emerging technologies that can improve extravasation care.

Main Methods:

  • Comprehensive literature review of pathophysiology, incidence, risk factors, clinical presentation, diagnosis, prevention, management, complications, and long-term effects of extravasation.
  • Exploration of current and emerging technologies for extravasation prevention and management.
  • Identification of research gaps and future directions.

Main Results:

  • Extravasation presents diverse challenges in cancer care, necessitating robust prevention and management strategies.
  • Emerging technologies, including advanced vein visualization, smart catheters, targeted drug delivery, novel topical treatments, and AI-based image analysis, show promise.
  • Ongoing research is crucial for refining prevention and management protocols.

Conclusions:

  • This review provides healthcare professionals with insights to enhance patient safety and optimize clinical practice regarding extravasation.
  • It underscores the importance of continued research and innovation in improving outcomes for cancer patients experiencing extravasation events.
  • Adoption of novel technologies is key to mitigating extravasation risks and improving patient care.