Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

215
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
215
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

321
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
321
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

134
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
134
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

231
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
231
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

177
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
177

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Antibacterial mechanisms of magnolol against Streptococcus agalactiae and immunomodulatory effects in Schizothorax prenanti.

Fish & shellfish immunology·2026
Same author

Pressure-Induced Crossover from Antiferromagnetism to Single-Band Superconductivity via Multiband Superconductivity in Quasi-1D CrZr<sub>4</sub>Te<sub>14</sub>.

Journal of the American Chemical Society·2026
Same author

Flooded cultivation improves grain yield and appearance quality while reducing nutritional quality in Shanlan upland rice (Oryza sativa L.).

Food chemistry·2026
Same author

Mechanistic dissection of SMARCA2/4 molecular glues reveals programmable switching between DCAF16 and FBXO22.

Cell chemical biology·2026
Same author

Discovery of Serum Exosomal Protein Biomarkers for Early- and Late-Stage Lung Cancer Through Comparative Proteomic Analysis.

Anti-cancer agents in medicinal chemistry·2026
Same author

The effects of hypoxia environment at high-altitudes on inflammation and angiogenesis in wound healing process:A meta-analysis and review.

Journal of tissue viability·2026

Related Experiment Video

Updated: Jun 21, 2025

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
06:23

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

4.8K

Destructive Cryptococcal Osteomyelitis Mimicking Tuberculous Spondylitis.

Yifan Zhou1, Xiaoli Huang1, Yufei Liu1

  • 1Department of Infectious Diseases, The First College of Clinical Medical Science, China Three Gorges University & Yichang Central People's Hospital, Yichang, Hubei, China.

The American Journal of Case Reports
|July 14, 2024
PubMed
Summary
This summary is machine-generated.

Cryptococcal osteomyelitis is a rare fungal infection. Early tissue biopsy is crucial for diagnosing this vertebral infection, differentiating it from other spinal conditions.

More Related Videos

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
03:47

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

209
Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
04:37

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections

Published on: February 2, 2024

780

Related Experiment Videos

Last Updated: Jun 21, 2025

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
06:23

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

4.8K
A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
03:47

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

209
Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
04:37

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections

Published on: February 2, 2024

780

Area of Science:

  • Infectious Diseases
  • Mycology
  • Orthopedics

Background:

  • Cryptococcosis is an opportunistic infection primarily impacting immunocompromised individuals.
  • It commonly affects the respiratory and central nervous systems.
  • Cryptococcal osteomyelitis, particularly vertebral involvement, is an uncommon presentation.

Observation:

  • A 56-year-old woman with a history of pulmonary tuberculosis presented with lower back pain and limited mobility.
  • Physical examination revealed thoracic vertebral tenderness and enlarged lymph nodes.
  • Computed tomography-guided biopsy confirmed Cryptococcus-induced granulomatous inflammation in the vertebrae.

Findings:

  • Treatment with amphotericin B and fluconazole led to symptom and lesion improvement.
  • The patient achieved a stable condition with negative serum cryptococcal antigen post-treatment.
  • Early diagnosis through tissue biopsy is vital for effective management.

Implications:

  • Vertebral cryptococcal osteomyelitis presents with nonspecific symptoms, mimicking tuberculous spondylitis or spinal tumors.
  • Prompt tissue biopsy is essential for accurate diagnosis and appropriate treatment selection.
  • This case highlights the importance of considering rare fungal infections in spinal pathology evaluations.