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Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

541
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
541
Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

10.8K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
10.8K

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Related Experiment Video

Updated: Jun 21, 2025

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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How do we conduct a national transfusion related lookback program?

Nicole Priddee1, Tiffany Pietrek2, Lorna McLintock1

  • 1Donor Services Division, Scottish National Blood Transfusion Service, Edinburgh, UK.

Transfusion
|July 14, 2024
PubMed
Summary
This summary is machine-generated.

A national hepatitis B lookback investigation in Scotland ensured recipient safety and provided reassurance. Key to success were a patient-centered approach, clear communication, and multiagency collaboration, despite challenges in stakeholder engagement.

Keywords:
Scotlandanti‐hepatitis B core screeningnational lookbackoccult hepatitis b infection (OBI)

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Area of Science:

  • Public Health
  • Infectious Disease Surveillance
  • Blood Transfusion Safety

Background:

  • Blood services conduct lookback investigations to mitigate infection transmission risks from donors to recipients.
  • A national lookback exercise in Scotland was prompted by the 2021 UK recommendation to test for occult hepatitis B infection.
  • This process involves tracing transfusion recipients and offering infectious agent testing.

Observation:

  • The study details the development and implementation of a national lookback program.
  • Logistical, economic, ethical, regulatory, and scientific considerations were integral to the planning and execution.
  • The program required robust governance, stakeholder engagement, and effective communication strategies.

Findings:

  • High testing uptake among recipients was achieved.
  • Low levels of participant anxiety were reported.
  • A comprehensive dataset was generated, offering valuable insights into the investigation's outcomes.

Implications:

  • Successful large-scale lookback programs necessitate a patient-centered strategy.
  • Clear, accessible communication and multiagency collaboration are crucial for effective delivery.
  • Stakeholder engagement and resource capacity present significant challenges in such initiatives.