Radiopathological Correlation in Orbital Lesions.

Area of Science:

• Ophthalmology
• Radiology
• Pathology

Background:

• Orbital lesions require accurate diagnosis for effective management.
• Radiological interpretation is crucial for initial assessment.
• Variability in diagnostic accuracy among radiologists can impact patient care.

Purpose of the Study:

• To compare the diagnostic accuracy of orbital imaging interpretation between specialized and general radiologists.
• To correlate radiological findings with histopathological diagnoses for orbital lesions.
• To evaluate the sensitivity, specificity, and predictive values in differentiating lesion types.

Main Methods:

• Retrospective review of 40 patients with orbital lesions over 7 years.
• Re-evaluation of pre-existing imaging by an in-house orbital imaging specialist.
• Comparison of diagnostic accuracy against histopathological findings and initial reports.
• Calculation of sensitivity, specificity, PPV, and NPV for lesion characterization.

Main Results:

• In-house specialist achieved 95% accuracy (κ=0.9) vs. 50% (κ=0.036) for extramural radiologists.
• Specialist's sensitivity/PPV: 93.31%/100% (benign), 95.24%/95.24% (malignant).
• Extramural radiologists' sensitivity/PPV: 76.92%/66.67% (benign), 14.28%/60% (malignant).

Conclusions:

• Radiologists with specialized orbital imaging experience achieve high diagnostic accuracy.
• Expert interpretation is key for reliable differentiation of orbital lesions.
• Specialized analysis improves sensitivity and positive predictive value for benign and malignant lesions.