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A Comparative In Vitro Physicochemical Analysis of Resin Infiltrants Doped With Bioactive Glasses.
Syed Zubairuddin Ahmed1, Abdul S Khan1, Naemah M Aljeshi2
1Restorative Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, SAU.
Cureus
|July 15, 2024
Summary
New bioactive glass (BAG) dental resin infiltrants show superior longevity and effectiveness compared to commercial options. Fluoride-substituted BAG demonstrated the highest microhardness and acid resistance in artificial saliva and pH cycling tests.
Area of Science:
- Dental Materials Science
- Biomaterials Engineering
- Restorative Dentistry
Background:
- Dental caries management often involves resin infiltrants to arrest lesion progression.
- Bioactive glasses (BAGs) are known for their remineralization potential and biocompatibility.
- Investigating BAG-based infiltrants for enhanced dental restorative material performance is crucial.
Purpose of the Study:
- To evaluate the longevity and effectiveness of experimental bioactive glass (BAG)-based dental resin infiltrants.
- To compare the performance of novel BAG infiltrants against commercial resin infiltrants (ICON®) and pure resin.
- To assess the impact of different BAG compositions (45S5, boron-substituted, fluoride-substituted) on material properties.
Main Methods:
- Experimental resin infiltrants were formulated by incorporating three types of BAG (45S5, boron-substituted, fluoride-substituted) with dimethacrylate monomers.
- Control groups included ICON® (CN) and pure resin (PR).
- Disc-shaped samples underwent 30-day challenges involving pH cycling and immersion in artificial saliva, with evaluations of Vicker's microhardness, surface roughness, and surface morphology at Day 0 and Day 30.
Main Results:
- The fluoride-substituted BAG (RIF) group exhibited the highest Vicker's microhardness after 30 days of artificial saliva immersion (78.20 ±0.06) and after pH cycling (64.15 ±1.89).
- Boron-substituted BAG (RIB) showed the highest surface roughness (1.14 ±0.001 µm) after artificial saliva immersion, while RIF showed the highest roughness after pH cycling (0.94 ±0.54 µm).
- Morphological analysis indicated smoother surfaces for RIB, CN, and PR after saliva immersion, but RIB and RIF demonstrated superior resistance to acid attack during pH cycling.
Conclusions:
- Experimental resin infiltrants incorporating BAGs, particularly the fluoride-substituted variant, demonstrate superior longevity and effectiveness compared to commercial ICON® infiltrants.
- BAG-based infiltrants show promising potential for enhanced performance in dental restorative applications, offering improved microhardness and acid resistance.
- Further research into optimizing BAG compositions and resin matrices could lead to advanced dental infiltrant materials.
