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Related Experiment Video

Updated: Jun 21, 2025

High-density Electroencephalographic Acquisition in a Rodent Model Using Low-cost and Open-source Resources

High-density Electroencephalographic Acquisition in a Rodent Model Using Low-cost and Open-source Resources

Published on: November 26, 2016

Engrams: From Behavior to Brain-Wide Networks.

Kaitlyn E Dorst^1,2,3, Steve Ramirez⁴

¹Department of Psychological and Brain Sciences, Boston University, Boston, MA, USA.

Advances in Neurobiology

|July 15, 2024

Summary

This summary is machine-generated.

Animals use brain-wide neural pathways for survival behaviors like fight, flight, or freeze. Recent technology allows scientists to study how memory engrams in the hippocampus influence these behaviors and brain states.

Keywords:

Activity pattern Brain Hippocampus Network

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Last Updated: Jun 21, 2025

High-density Electroencephalographic Acquisition in a Rodent Model Using Low-cost and Open-source Resources

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Published on: November 26, 2016

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Published on: March 8, 2024

3D Scanning Technology Bridging Microcircuits and Macroscale Brain Images in 3D Novel Embedding Overlapping Protocol

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Published on: May 12, 2019

Area of Science:

Neuroscience
Behavioral Biology
Cognitive Science

Background:

Animals exhibit diverse behaviors for survival, including fight, flight, or freeze responses.
These behaviors are guided by real-time computations integrating internal and environmental states.
The hippocampus is crucial for encoding and recalling experiences as memory engrams.

Purpose of the Study:

To review technological advancements for studying memory engrams.
To explore how hippocampal memory engrams influence brain-wide states and behavior.
To connect cellular activity to cognition and behavior through memory engram research.

Main Methods:

Overview of recent technologies for tagging, manipulating, and visualizing neural ensembles (engrams).
Discussion of experimental approaches to link engram activity to behavioral outcomes.
Analysis of how environmental context influences engram-mediated behavior.

Main Results:

Recent technologies enable detailed study of memory engrams.
Hippocampal fear engrams modulate behavior based on environmental features.
Engrams influence brain-wide cellular activity patterns.

Conclusions:

Memory engrams provide a framework for linking neural activity to cognition and behavior.
Understanding engrams offers insights into how the brain organizes experiences.
Future research can causally connect brain-wide neural underpinnings to behavior.