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Cutaneous Involvement by Refractory Celiac Disease Type 2 Histologically Mimicking Mycosis Fungoides
Angela Mei1, Benjamin Allanson2, Dustin Hall3
1Sir Charles Gairdner Hospital, Perth, Australia.
The American Journal of Dermatopathology
|July 15, 2024
Summary
Refractory celiac disease type 2 can manifest with rare skin lesions due to abnormal T-lymphocytes. This case highlights cutaneous involvement in RCD type 2, a condition with high lymphoma transformation risk.
Area of Science:
- Gastroenterology
- Dermatology
- Immunology
Background:
- Refractory celiac disease (RCD) involves persistent symptoms despite a gluten-free diet.
- RCD type 2 is characterized by aberrant intraepithelial T lymphocytes and can progress to enteropathy-associated T-cell lymphoma (EATL).
- Cutaneous manifestations of RCD type 2 are rare, with limited histopathological documentation.
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