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Related Concept Videos

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Archival Research

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Some researchers gain access to large amounts of data without interacting with a single research participant. Instead, they use existing records to answer various research questions. This type of research approach is known as archival research. Archival research relies on looking at past records or data sets to look for interesting patterns or relationships. For example, a researcher might access the academic records of all individuals who enrolled in college within the past ten years and...
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Gravimetry: Inorganic And Organic Precipitating Agents00:49

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In gravimetry, the precipitant is chosen carefully to obtain a pure solid that can be easily filtered. Common inorganic precipitants can be used to determine several cations and anions. In some cases, the formation of the same precipitate can be used to determine the cation and the anion. For example, the reaction of barium and chromate ions to give barium chromate is used to determine both barium and chromate. However, precipitates such as hydroxides, oxalates, and metal ammonium phosphates...
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Mass Spectrometry: Alcohol Fragmentation01:03

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Alcohols (R-OH) ionize to lose one non-bonded electron from the oxygen atom, forming molecular ions. Due to their tendency to fragment rapidly, the intensity of the molecular ion peak in the mass spectrum is weak or sometimes absent. The fragmentation patterns for alcohols occur in two ways, i.e. ⍺-cleavage and dehydration. During ⍺-cleavage, the bond at the ⍺-position adjacent to the hydroxyl group cleaves to give a resonance-stabilized cation and a radical. However,...
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Updated: Jun 21, 2025

The Terroir Concept Interpreted through Grape Berry Metabolomics and Transcriptomics
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GRAPPA 2023 Collaborative Research Network Meeting.

Vinod Chandran1, Dafna D Gladman2, Philip J Mease3

  • 1V. Chandran, MBBS, MD, DM, PhD, Division of Rheumatology, Departments of Medicine and Laboratory Medicine and Pathobiology, University of Toronto, and Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.

The Journal of Rheumatology
|July 15, 2024
PubMed
Summary
This summary is machine-generated.

The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) research committee met to discuss ongoing projects. A key focus was the integration of digital tools for advancing psoriatic disease research.

Keywords:
GRAPPAbiomarkerspsoriasispsoriatic arthritisspondyloarthritis

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Area of Science:

  • Rheumatology and Dermatology
  • Psoriatic Disease Research

Background:

  • The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) Collaborative Research Network (CRN) convened for its annual meeting.
  • The meeting focused on updates from various GRAPPA research initiatives.

Framework:

  • Key GRAPPA projects discussed included Axial Involvement in Psoriatic Arthritis (AXIS), Axial Psoriatic Arthritis Molecular and Clinical Characterisation Study, Diagnostic Ultrasound Enthesitis Tool (DUET), and Sex- and Gender-Based Analysis of the Effectiveness of Advanced Therapies (SAGE).
  • Further updates were provided on the Health Initiatives in Psoriasis and Psoriatic Arthritis Consortium European States (HIPPOCRATES) and Elucidating the Landscape of Immunoendotypes in Psoriatic Skin and Synovium (ELLIPSS) studies.

Implementation:

  • The GRAPPA CRN/research committee meeting facilitated progress updates on multiple psoriatic disease research projects.
  • Discussions covered a range of studies investigating axial involvement, molecular and clinical characterization, diagnostic tools, treatment effectiveness, health initiatives, and immunoendotypes.

Implications:

  • The integration of digital tools emerged as a significant theme, highlighting their potential to enhance the study of psoriatic disease.
  • These advancements promise to improve understanding and management of psoriasis and psoriatic arthritis through collaborative research and technological innovation.