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DBScope as a versatile computational toolbox for the visualization and analysis of sensing data from deep brain

Andreia M Oliveira1,2, Eduardo Carvalho1,3, Beatriz Barros1,2

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A new open-source toolbox, DBScope, helps analyze deep brain stimulation (DBS) sensing data. This tool aids clinicians and researchers in understanding brain activity and developing adaptive therapies.

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Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Medical Technology

Background:

  • Chronic sensing of local field potentials (LFPs) during deep brain stimulation (DBS) offers new insights into neurological disorders.
  • Limited tools exist for visualizing and analyzing this rich LFP data from modern DBS neurostimulators.

Purpose of the Study:

  • To introduce DBScope, a free, open-source toolbox designed to import, visualize, and analyze DBS sensing data.
  • To provide a versatile solution for both clinical and research applications, facilitating biomarker discovery and adaptive stimulation.

Main Methods:

  • Development of a software toolbox (DBScope) with both a graphical user interface (GUI) and a programmatic library.
  • Importing and processing of chronic LFP data from various neurostimulation devices.

Main Results:

  • DBScope enables efficient data inspection for clinical decision-making.
  • The toolbox supports research pipelines for pre-processing, feature extraction, and biomarker identification.
  • DBScope is actively used in clinical and research settings.

Conclusions:

  • DBScope addresses the need for accessible tools to exploit DBS sensing data.
  • The toolbox can accelerate the identification of electrophysiological biomarkers and the advancement of adaptive DBS therapies.
  • DBScope is freely available on GitHub with comprehensive documentation.