A Study on Nonvibration-Exposed Organs Correlated Indices as Diagnostic Biomarkers of Hand-Arm Vibration Syndrome
Related Experiment Video
Updated: Jun 21, 2025
Measurement of the Hand Transmitted Vibration of the Human Hand Arm System During Operation of a Hand Tractor
Published on: June 16, 2021
Kanshou Zhou1, Fanfei Zeng, Siheng Wu
1From the Guangdong Pharmaceutical University, Guangzhou, Guangdong Province, China (KZ, FZ, SW, YZ, QC, HY); and Guangdong Provincial Engineering Research Center of Public Health Detection and Assessment, Guangzhou, Guangdong Province, China (KZ, FZ, SW, YZ, QC, HY).
Objective:
The aim of the study is to explore the feasibility of using nonvibration-exposed organ-related indices as vibration-induced white finger (VWF) diagnostic biomarkers.
Methods:
Individuals were selected from a factory in China using the judgment sampling method. They were divided into control (con), non-VWF, and VWF groups according to the presence/absence of exposure to hand-transmitted vibration and VWF. Blood samples were collected for ELISA tests.
Results:
Analysis of receiver operating characteristic curves was done on six indicators to assess their diagnostic sensitivity for VWF. Area under the receiver operating characteristic curve for insulin was 0.909 and was 0.923 for aspartate aminotransferase.
Conclusions:
Insulin and aspartate aminotransferase could be used as indices for the diagnosis of hand-arm vibration syndrome.
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