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Updated: Jun 21, 2025
Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Correlation between coronary artery calcification and COVID-19
Saeed Abrotan1, Seyed Farzad Jalali1, Mohammadtaghi Hedayati-Godarzi1
1Department of Cardiology, School of Medicine, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.
Insights
Coronary artery calcification (CAC) is linked to in-hospital mortality in COVID-19 patients. This study found CAC correlates with various clinical factors but not COVID-19 severity, and it did not significantly predict mortality.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Imaging
Background:
- Coronary heart disease (CHD) increases COVID-19 mortality and morbidity.
- Coronary artery calcification (CAC) is a diagnostic method for CHD.
- Investigating CAC in COVID-19 patients is crucial for understanding outcomes.
Purpose of the Study:
- To explore the association between CAC and clinical findings in COVID-19 patients.
- To determine the relationship between CAC and COVID-19 severity.
- To assess the link between CAC and in-hospital outcomes, including mortality.
Main Methods:
- Retrospective study of 551 suspected COVID-19 patients.
- Data collection included comorbidities, clinical exams, lab tests, and hospitalization details.
- Analysis focused on correlations between CAC and various clinical parameters and outcomes.
Main Results:
- A significant relationship was found between CAC and in-hospital mortality.
- CAC correlated with age, hospitalization duration, pulse rate, blood pressure, ESR, BUN, WBC, and oxygen saturation.
- No significant association was observed between CAC and COVID-19 severity index; CAC did not significantly predict mortality.
Conclusions:
- CAC is significantly related to in-hospital mortality in COVID-19 patients.
- While CAC correlates with several clinical markers, its predictive value for mortality in this cohort was not significant.
- Further research may clarify the role of CAC in COVID-19 prognosis.
Background:
Coronary heart disease (CHD) is an underlying cardiac condition contributing to increased COVID-19 mortality and morbidity which can be assessed by several diagnosis methods including coronary artery calcification (CAC). The goal of this study was to find out if there were potential links between CAC, clinical findings, severity of COVID-19, and in-hospital outcomes.
Methods:
This retrospective study evaluated 551 suspected patients admitted to teaching hospitals of the Babol University of Medical Sciences, Babol, Iran, from March to October 2021. Data included previous diseases, comorbidities, clinical examinations, routine laboratory tests, demographic characteristics, duration of hospitalization, and number of days under ventilation were recorded in a checklist.
Results:
Findings of current study provide evidence of a significant relationship between coronary artery calcification (CAC) and in-hospital mortality. Additionally, we observed significant correlations between CAC and several clinical parameters including age, duration of hospitalization, pulse rate, maximum blood pressure, erythrocyte sedimentation rate (ESR), blood urea nitrogen (BUN), neutrophil count, white blood cell (WBC) count, and oxygen saturation. However, we did not observe a significant association between CAC and the severity index of COVID-19. In addition, logistic regression tests did not find a significant value of CAC to predict in-hospital mortality.
Conclusion:
Our findings showed a significant relationship between CAC and in-hospital mortality.
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