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Related Experiment Video

Updated: Jun 21, 2025

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
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Correlation between coronary artery calcification and COVID-19.

Saeed Abrotan1, Seyed Farzad Jalali1, Mohammadtaghi Hedayati-Godarzi1

  • 1Department of Cardiology, School of Medicine, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.

Caspian Journal of Internal Medicine
|July 16, 2024
PubMed
Summary

Coronary artery calcification (CAC) is linked to in-hospital mortality in COVID-19 patients. This study found CAC correlates with various clinical factors but not COVID-19 severity, and it did not significantly predict mortality.

Keywords:
COVID-19Coronary artery calcificationCoronary heart diseaseHospitalizationMorbidityMortality

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Area of Science:

  • Cardiology
  • Infectious Diseases
  • Medical Imaging

Background:

  • Coronary heart disease (CHD) increases COVID-19 mortality and morbidity.
  • Coronary artery calcification (CAC) is a diagnostic method for CHD.
  • Investigating CAC in COVID-19 patients is crucial for understanding outcomes.

Purpose of the Study:

  • To explore the association between CAC and clinical findings in COVID-19 patients.
  • To determine the relationship between CAC and COVID-19 severity.
  • To assess the link between CAC and in-hospital outcomes, including mortality.

Main Methods:

  • Retrospective study of 551 suspected COVID-19 patients.
  • Data collection included comorbidities, clinical exams, lab tests, and hospitalization details.
  • Analysis focused on correlations between CAC and various clinical parameters and outcomes.

Main Results:

  • A significant relationship was found between CAC and in-hospital mortality.
  • CAC correlated with age, hospitalization duration, pulse rate, blood pressure, ESR, BUN, WBC, and oxygen saturation.
  • No significant association was observed between CAC and COVID-19 severity index; CAC did not significantly predict mortality.

Conclusions:

  • CAC is significantly related to in-hospital mortality in COVID-19 patients.
  • While CAC correlates with several clinical markers, its predictive value for mortality in this cohort was not significant.
  • Further research may clarify the role of CAC in COVID-19 prognosis.