Extraordinary model systems for regeneration

Area of Science:

• Regenerative Biology
• Developmental Biology
• Comparative Biology

Background:

• Regeneration enables organisms to regrow complex structures like limbs.
• A 2019 collection introduced popular model organisms for in vivo regeneration studies.
• Further exploration is needed to showcase less common, yet extraordinary, species.

Purpose of the Study:

• To expand the understanding of model systems for regeneration.
• To highlight underutilized species in regenerative biology research.
• To present expert insights on novel regenerative models.

Main Methods:

• Perspective piece featuring interviews with five expert biologists.
• Showcasing less well-known species for regeneration research.
• In vivo studies of regenerative capabilities in diverse organisms.

Main Results:

• Introduction of several extraordinary, less-studied species for regeneration research.
• Expert perspectives on the unique advantages of these novel models.
• Emphasis on the diversity of regenerative strategies across the animal kingdom.

Conclusions:

• Expanding the repertoire of model organisms can accelerate regenerative biology.
• Studying diverse species offers broader insights into regeneration mechanisms.
• Novel models provide unique opportunities to understand biological repair and regrowth.