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Effectiveness of BNT162b2 XBB Vaccine Against XBB and JN.1 Sublineages
Sara Y Tartof1, Jeff M Slezak1, Laura Puzniak2
1Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California, USA.
Open Forum Infectious Diseases
|July 17, 2024
Abstract:
We provide updated results (11 October 2023 through 29 February 2024) from our previously conducted test-negative case-control study in Kaiser Permanente Southern California to evaluate sublineage-specific effectiveness of the BNT162b2 XBB1.5-adapted vaccine. Results suggest that XBB1.5-adapted vaccines may have reduced effectiveness against JN.1 versus XBB sublineages.
