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Bone Remodeling and Repair

Bone Remodeling and Repair

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...

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Related Experiment Video

Updated: Jun 26, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Curriculum for training in orthobiologics

Michael Auriemma¹, Haylee Borgstrom², David Itskevich³

¹Regenerative Orthopedics and Sports Medicine, North Bethesda, Maryland, USA.

PM & R : the Journal of Injury, Function, and Rehabilitation

|July 17, 2024

Summary

No abstract available in PubMed .

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