Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

459
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
459
Drug Dependence01:17

Drug Dependence

993
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
993
CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

195
Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
195
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

163
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
163
Analgesia and Pain Management01:25

Analgesia and Pain Management

561
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
561
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

714
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
714

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Leveraging barbershops for community-based addiction research: A pilot study using hair samples to detect fentanyl and stress biomarkers.

Journal of substance use and addiction treatment·2026
Same author

The Future of <i>DSM</i>: Response to Letters.

The American journal of psychiatry·2026
Same author

County-Level Variation in Substance Use Disorder Service Utilization by Insurance Payers and Self-Pay in the United States.

The Journal of clinical psychiatry·2026
Same author

Non-Indigenous women's experiences of obstetric and gynaecological inequity in rural and remote South Australia: A feminist post-structuralist analysis.

Women's health (London, England)·2026
Same author

Polysubstance use disorders among US adults.

Molecular psychiatry·2026
Same author

Utilizing the Practical Robust, Implementation and Sustainability Model to Explore the Primary Care Setting Contextual Determinants of Implementing Patient-Reported Outcomes Measures to Support Opioid Use Disorder Care.

Implementation research and practice·2026

Related Experiment Video

Updated: Jun 20, 2025

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
09:29

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods

Published on: August 4, 2022

2.2K

Physician Reluctance to Intervene in Addiction: A Systematic Review.

Melinda Campopiano von Klimo1, Laura Nolan1, Michelle Corbin2

  • 1JBS International, Inc, North Bethesda, Maryland.

JAMA Network Open
|July 17, 2024
PubMed
Summary

Physicians hesitate to adopt evidence-based practices (EBPs) for substance use disorder due to lack of institutional support, knowledge, and skills. Addressing these barriers can improve addiction care and physician adoption of EBPs.

More Related Videos

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

885
Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
07:31

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice

Published on: January 7, 2019

7.9K

Related Experiment Videos

Last Updated: Jun 20, 2025

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
09:29

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods

Published on: August 4, 2022

2.2K
Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

885
Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
07:31

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice

Published on: January 7, 2019

7.9K

Area of Science:

  • Addiction Medicine
  • Public Health
  • Physician Education

Background:

  • The US faces an ongoing overdose epidemic, with over 107,000 deaths in 2022.
  • Physician adoption of evidence-based practices (EBPs) for substance use disorder (SUD) remains low despite training efforts.

Purpose of the Study:

  • To identify physician-reported reasons for reluctance in addressing substance use and addiction.
  • To explore physician barriers to implementing screening, treatment, harm reduction, and recovery support interventions.

Main Methods:

  • Systematic review of literature from 1960-2021, adhering to PRISMA guidelines.
  • Inclusion of 183 studies reporting data from 66,732 physicians.
  • Utilized the theoretical domains framework for data extraction.

Main Results:

  • Lack of institutional support (81.2%), knowledge (71.9%), skill (73.9%), and cognitive capacity (73.5%) were the most common reasons for physician reluctance.
  • Reimbursement concerns were also identified.
  • Reasons for reluctance were associated with physician specialty, intervention type, and drug type.

Conclusions:

  • Addressing physician reluctance requires targeting institutional support, knowledge gaps, skill deficits, and cognitive capacity.
  • Implementing educational initiatives, policy development, and program support can enhance EBP adoption.
  • Future research should focus on validated survey instruments and theoretical frameworks to improve understanding of physician barriers.