Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is Genetic Engineering?00:49

What is Genetic Engineering?

74.0K
Overview
74.0K
Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

5.6K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.6K
Human Genetics01:28

Human Genetics

556
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
556
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

351
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
351
DNA Microarrays02:34

DNA Microarrays

17.3K
Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
17.3K
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

13.3K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
13.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

From evidence to implementation: key priorities for pharmacogenomics-guided treatment and prevention from a European expert workshop.

European journal of human genetics : EJHG·2026
Same author

Towards responsible genome-wide screening: normative and stakeholder considerations.

European journal of human genetics : EJHG·2026
Same author

Digital genetic counseling services for cascade cardiogenetic testing.

Journal of genetic counseling·2026
Same author

A Multi-Stakeholder Perspective on Integrating Genomic Sequencing into Newborn Screening: An Interview Study.

International journal of neonatal screening·2026
Same author

Dutch Christian Faith Leaders Deliberating Human Germline Gene Editing: A Qualitative Study.

Journal of religion and health·2026
Same author

Values of Individuals With Rare Genetic Neurodevelopmental Disorders and Their Family/Caregivers in Healthcare: A Scoping Review to Inform Guideline Development.

Journal of intellectual disability research : JIDR·2026

Related Experiment Video

Updated: Jun 20, 2025

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.1K

Policy Guidance for Direct-to-Consumer Genetic Testing Services: Framework Development Study.

Suzanne Maria Onstwedder1,2,3, Marleen Elizabeth Jansen1,2,3, Martina Cornelia Cornel2,3

  • 1Department of Public Health Genomics and Screening, Centre for Health Protection, Dutch National Institute for Public Health and the Environment, Bilthoven, Netherlands.

Journal of Medical Internet Research
|July 17, 2024
PubMed
Summary

Direct-to-consumer genetic tests (DTC-GTs) offer health insights but lack policy guidance. This study developed a framework and checklist to assess DTC-GT services, aiding policymakers in balancing safety and autonomy.

Keywords:
direct-to-consumer testinggenetic privacygenetic testinghealth policyinformed consentmHealthmobile healthonline marketpolicy decisionprivacypublic health genomics

More Related Videos

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform
09:30

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

3.1K
Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
11:35

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

Published on: August 21, 2016

12.9K

Related Experiment Videos

Last Updated: Jun 20, 2025

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.1K
Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform
09:30

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

3.1K
Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
11:35

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

Published on: August 21, 2016

12.9K

Area of Science:

  • Genetics and Public Health
  • Bioethics and Policy
  • Consumer Health Informatics

Background:

  • Direct-to-consumer genetic tests (DTC-GTs) provide genetic insights but raise safety and autonomy concerns.
  • A lack of assessment tools hinders effective policy-making for DTC-GT services.
  • Uncertainty exists regarding the responsibilities of policymakers, regulators, and law enforcers in the DTC-GT market.

Purpose of the Study:

  • To develop a framework identifying policy-relevant aspects of DTC-GT services.
  • To provide policy guidance for regulating DTC-GTs.
  • To address the need for instruments to assess DTC-GT services.

Main Methods:

  • An integrative literature review (Embase, Medline, Jan 2014-June 2022) identified DTC-GT risks and benefits.
  • Consumer journey phases were defined to structure identified risks and benefits.
  • A checklist with 8 themes and 38 items was developed for policy guidance.

Main Results:

  • 134 papers were analyzed, mapping risks and benefits across 6 consumer journey phases: exposure, pretest information, DNA analysis, data management, posttest information, and impact.
  • A checklist was created, comprising 8 themes and 38 items relevant to policy issues.
  • Key themes included service content, validity, data privacy, scientific robustness, and information quality.

Conclusions:

  • The consumer journey and checklist dissect DTC-GT offers into critical components.
  • The framework aids policymakers, regulators, and law enforcers in evaluating and managing the DTC-GT market.
  • This approach supports safeguarding individual and public health, safety, and autonomy.