Dutch Christian Faith Leaders Deliberating Human Germline Gene Editing: A Qualitative Study

Area of Science:

• Bioethics
• Religious Studies
• Gene Editing

Background:

• Public dialogue on human germline gene editing (HGGE) is crucial for clarifying ethical values.
• Christian values may significantly influence perspectives on HGGE within religious communities and society.
• Existing regulations prohibit HGGE, necessitating exploration of underlying ethical considerations.

Purpose of the Study:

• To explore the views and underlying values of Dutch Christian faith leaders regarding HGGE.
• To understand their approaches to pastoral counseling concerning HGGE.
• To gather recommendations for future legislation on HGGE.

Main Methods:

• Conducted in-depth interviews with 16 Dutch Christian faith leaders between 2019 and 2024.
• Employed reflexive thematic analysis to interpret interview data.
• Focused on participants' perspectives on HGGE acceptability, pastoral care, and legislative recommendations.

Main Results:

• Six core values underpin views on HGGE: human dignity, humility, alleviation of suffering, acceptance, compassion, and justice.
• Faith leaders would offer unconditional support in pastoral counseling while guiding reflection on motivations for HGGE.
• Concerns were raised about a slippery slope from therapeutic use to enhancement, urging cautious legislation.

Conclusions:

• HGGE views are shaped by fundamental ethical and religious values.
• Pastoral care for HGGE-related issues requires balancing unconditional support with value-guided reflection.
• Future legislation should prioritize caution and prohibit human enhancement to prevent unintended consequences.