Related Experiment Video
Updated: Jun 20, 2025
A Mouse Model of Intestinal Partial Obstruction
Published on: March 5, 2018
Poorly Cohesive Carcinoma of the Nonampullary Small Bowel: A Rare Cause of Recurrent Small Bowel Obstruction
Brian J Lee1, Jesus Guzman2, Osvaldo Padilla3
1Department of Internal Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, TX.
Abstract:
Poorly cohesive carcinoma (PCC) is an uncommon neoplasm characterized by tumorous cells exhibiting a lack of adhesion. PCC has been reported rarely in the small intestine other than at the ampulla of Vater. We present a 40-year-old man with recurrent abdominal pain and small bowel obstruction. Imaging revealed an abnormal appearing distal small bowel, with only nonspecific mucosal changes discovered on antegrade and retrograde enteroscopy. On subsequent diagnostic laparoscopy, an ileal mass was found and resected with histopathology showing PCC with signet ring formation. This is an aggressive cancer with a worse prognosis than other small bowel adenocarcinomas.
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