Related Experiment Video
Updated: Jun 20, 2025

07:44
Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
5.7K
Combination of Precut Techniques in Difficult Biliary Cannulation
Azar Abiyev1, Barış Tuzcu2, Gülden Bilican3
1Department of Gastroenterology, Private Koru Hospital, Ankara, Turkey.
Euroasian Journal of Hepato-Gastroenterology
|July 18, 2024
Summary
Combining transpancreatic septotomy (TPS) and needle-knife sphincterotomy (NKS) improved selective biliary cannulation success rates in difficult endoscopic retrograde cholangiopancreatography (ERCP) cases. This combined approach offers a higher success rate than using TPS alone.
Area of Science:
- Gastroenterology
- Endoscopy
- Surgical Techniques
Background:
- Selective biliary cannulation (SBC) is crucial for successful ERCP.
- Standard SBC fails in up to 20% of cases, necessitating precut techniques.
- Needle-knife sphincterotomy (NKS) and transpancreatic septotomy (TPS) are common precut methods, but can also fail.
Purpose of the Study:
- To evaluate the procedural success of a combined TPS + NKS technique for difficult biliary cannulation during ERCP.
- To compare the efficacy of combined precut techniques against individual precut methods.
Main Methods:
- Retrospective analysis of 289 patients undergoing ERCP with precut techniques (2017-2022).
- Patients were grouped into: Transpancreatic septotomy (TPS) only, Needle-knife sphincterotomy (NKS) only, and combined TPS + NKS.
- Evaluated cannulation success rates and ERCP-related adverse effects.
Main Results:
- The TPS + NKS group achieved an 87% SBC success rate, compared to 69% for TPS alone and 75.3% for NKS alone.
- Cannulation success was significantly higher in both NKS and TPS + NKS groups compared to the TPS group (p < 0.001).
- ERCP-related complication rates were similar across all groups.
Conclusions:
- A second precut technique, such as combining TPS and NKS, can be effective when initial precut methods fail.
- Previous TPS does not preclude the successful use of NKS.
- The combined TPS + NKS technique offers an improved success rate for challenging biliary cannulation during ERCP.

