Risk Factors Associated with Postoperative Nausea and Vomiting After Esophagogastroduodenoscopy.

Area of Science:

• Gastroenterology
• Anesthesiology
• Clinical Research

Background:

• Postoperative nausea and vomiting (PONV) is a frequent complication impacting patient recovery after sedation.
• Data on PONV incidence and risk factors following esophagogastroduodenoscopy (EGD) are limited.
• Understanding PONV predictors is crucial for improving patient comfort and outcomes.

Purpose of the Study:

• To determine the incidence of PONV after EGD performed under sedation.
• To identify patient-specific and procedural factors associated with PONV development.

Main Methods:

• Retrospective analysis of 152 adult patients undergoing elective EGD under sedation.
• Data collection included demographics, Apfel risk scores, sedative agents, procedure details, and endoscopic findings.
• PONV assessment occurred during the post-anesthesia care unit stay.

Main Results:

• PONV incidence was 8.6% (13 patients).
• Significant risk factors identified: female sex, higher BMI, preoperative nausea/vomiting, thyroid disease, oral antidiabetic drug use, and higher Apfel scores.
• No significant association found with age, ASA score, procedure duration, sedative agents, or endoscopic findings.

Conclusions:

• PONV following EGD under sedation is relatively uncommon.
• Patient-related factors such as female sex, elevated BMI, preoperative nausea, thyroid disease, oral antidiabetic drug use, and higher Apfel risk scores are associated with increased PONV risk.
• Further research can focus on targeted PONV prophylaxis in high-risk EGD patients.