Consensus Statement: Technical Standards for Thoracoabdominal Normothermic Regional Perfusion.

Area of Science:

• Transplantation Surgery
• Organ Procurement
• Medical Device Technology

Background:

• Thoracoabdominal normothermic regional perfusion (TA-NRP) is a key technique for optimizing organ procurement from donation after circulatory death (DCD) donors.
• Lack of standardized guidelines for TA-NRP implementation necessitates consensus recommendations for safe and effective use.

Purpose of the Study:

• To develop technical guidelines for TA-NRP implementation.
• To ensure safe, effective, and ethical utilization of TA-NRP in organ procurement.

Main Methods:

• A working group from major surgical societies systematically reviewed literature, consensus statements, and expert opinions.
• Key areas for standardization were identified, including predonation evaluation, intraoperative management, and postdonation procedures.

Main Results:

• Recommendations were formulated for donor evaluation, selection criteria, premortem interventions, communication, and procedural guidelines.
• These guidelines aim to improve coordination, minimize practice variability, and enhance transparency in TA-NRP processes.

Conclusions:

• The developed consensus guidelines provide a framework for implementing TA-NRP programs for DCD organ procurement.
• These recommendations are expected to enhance the quality, safety, and efficiency of TA-NRP, leading to better transplant recipient outcomes.