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Published on: February 1, 2022
Electrochemical detection of nitrofurazone using laser-engraved three-electrode graphene array
Xingyue Jiang1, Jiaxi Yin2, Lingbo Liu3
1Hubei Province Key Laboratory of Biotechnology of Chinese Traditional Medicine, College of Health Science and Engineering, Hubei University, Wuhan, 430062, China; College of Chemistry and Chemical Engineering, Hubei University, Wuhan, 430062, China.
A novel electrochemical sensor using laser-engraved graphene arrays offers a sensitive and practical method for detecting Nitrofurazone (NFZ) residues. This advancement improves upon existing methods, providing a reliable tool for food safety analysis.
Area of Science:
- Electrochemistry
- Materials Science
- Analytical Chemistry
Background:
- Nitrofurazone (NFZ) is an antimicrobial used in aquaculture.
- NFZ residues pose health risks (carcinogenesis, teratogenesis) via the food chain.
- Existing NFZ detection methods lack sensitivity and simplicity.
Purpose of the Study:
- To develop a highly sensitive, simple, and practical electrochemical sensor for NFZ detection.
- To overcome limitations of current NFZ detection techniques.
Main Methods:
- Fabrication of integrated three-electrode arrays using laser engraving on polyimide tape.
- Preparation and characterization of porous graphene arrays at varying laser power percentages.
- Electrochemical performance evaluation of the fabricated graphene arrays for NFZ oxidation.
Main Results:
- Laser-engraved graphene array (LIG-50) at 50% laser power showed superior performance due to its 3D structure, porosity, and stability.
- The LIG-50 sensor exhibited enhanced sensitivity for NFZ oxidation.
- Achieved a linear detection range of 0.2–8 μM with a detection limit of 0.035 μM.
- Successfully applied the sensor to detect NFZ in fish meat samples.
Conclusions:
- A sensitive, portable, and practical electrochemical sensor for NFZ detection was successfully developed using laser-engraved graphene arrays.
- The sensor demonstrates good accuracy and potential for real-world applications in food safety.
- This approach offers a new pathway for designing high-performance electrochemical sensors for diverse applications.
