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Cyclic vomiting syndrome: From pathophysiology to treatment
R A Jiménez-Castillo1, R Frazier2, T Venkatesan3
1Servicio de Gastroenterología y Endoscopía Digestiva, Hospital Universitario «Dr. José E. González», Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.
Revista De Gastroenterologia De Mexico (English)
|July 21, 2024
Summary
Cyclic vomiting syndrome (CVS) involves recurrent vomiting episodes. Research explores its causes, diagnosis, and management, highlighting the need for personalized, multidisciplinary treatment approaches.
Area of Science:
- Gastroenterology
- Pediatrics
- Neurology
Background:
- Cyclic vomiting syndrome (CVS) is a disorder of recurrent, intense vomiting episodes.
- Primarily affects children and adolescents, but can persist into adulthood.
- Significant impact on patient quality of life.
Purpose of the Study:
- Review epidemiology, pathophysiology, subtypes, diagnostic criteria, and management of CVS.
- Examine postulated triggers including genetic, nervous system, and environmental factors.
- Discuss current diagnostic challenges and treatment strategies.
Main Methods:
- Literature review of recent studies on CVS.
- Analysis of epidemiological data.
- Synthesis of current understanding of pathophysiology and management.
Main Results:
- Etiology remains unknown; potential triggers include genetic factors, autonomic dysregulation, and cannabinoid use.
- No specific diagnostic test exists, requiring thorough symptom evaluation and exclusion of other causes.
- Management involves a multidisciplinary approach with pharmacologic and psychologic therapies.
Conclusions:
- CVS presents diagnostic and therapeutic challenges.
- Personalized treatment is crucial for improving patient outcomes.
- Further research is needed for more effective strategies.
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