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Updated: Jun 20, 2025
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Blood Transfusion Reaction Reporting at a Tertiary Care Hospital: A Cross Sectional Study
Kavi Manasa1, Gurudutta Pattnaik2, Y Madhusudan Rao3
1Department of Pharmacy Practice, Centurion University of Technology and Management, Orissa, India.
Summary
Acute transfusion reactions (ATRs) occurred in 6.6% of patients. Factors like prior transfusion history, abortion history, and older stored blood increased ATR risk. Monitoring patients receiving multiple units is crucial.
Area of Science:
- Transfusion Medicine
- Patient Safety
- Clinical Hematology
Background:
- Blood transfusion is vital for oxygenation and hemostasis.
- Transfusions carry risks of complications influenced by various factors.
Purpose of the Study:
- To evaluate blood transfusion complications.
- To identify associated risk factors in adult patients.
Main Methods:
- Cross-sectional study of 182 adult patients.
- Data collected via questionnaires and record extraction.
- Blood and urine samples analyzed for complications; statistical analysis performed.
Main Results:
- Acute transfusion reactions (ATRs) observed in 6.6% of patients.
- Increased likelihood of ATRs associated with transfusion history, abortion history, and blood stored >20 days.
- Each additional blood unit transfused increased ATR odds by 2.07.
Conclusions:
- High incidence of acute transfusion reactions noted.
- Close patient monitoring is essential, especially for those with prior transfusions, abortion history, or receiving older blood.
- Careful management of patients receiving multiple blood units is recommended.
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