Related Experiment Video
Updated: Aug 19, 2026
08:40
Establishment and Characterization of UTI and CAUTI in a Mouse Model
Published on: June 23, 2015
[Masked obstructive uropathy of the upper urinary tract in childhood]
Insights
Congenital ureteropelvic junction obstruction is a common childhood urinary issue. Key symptoms include abdominal masses in infants and pain in older children, with hematuria also noted.
Area of Science:
- Pediatric Urology
- Medical Diagnostics
Background:
- Congenital ureteropelvic junction obstruction is the most frequent cause of urinary tract obstruction in pediatric patients.
- Understanding the varied presentations is crucial for timely diagnosis and intervention.
Observation:
- Infants often present with an abdominal mass.
- Older children may experience loin or abdominal pain, particularly after consuming fluids.
- Posttraumatic hematuria can be the sole presenting symptom in some cases.
Findings:
- The study highlights common clinical manifestations of congenital ureteropelvic junction obstruction.
- Diagnostic procedures are recommended to identify this condition effectively.
Implications:
- Early identification of ureteropelvic junction obstruction can prevent long-term renal damage.
- Prompt diagnostic workup is essential for managing pediatric urinary tract obstructions.
Abstract:
Congenital ureteropelvic junction obstruction is the most common site of urinary tract obstruction in children. In infants an abdominal mass, in older children loin or abdominal pain, especially after fluid intake, are commonly the presenting features. In some cases the only symptom is posttraumatic hematuria. Appropriate diagnostic procedures are suggested.
Related Concept Videos
01:20Disorders of the Urinary System
The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
01:11Anatomy of the Genitourinary System I: Kidneys and Ureters
The upper urinary system comprises two kidneys and two ureters, which are crucial in filtering blood and forming urine.KidneysLocation and Structure:The kidneys are two bean-shaped organs positioned behind the peritoneum on either side of the spine.Kidneys are between the 12th thoracic (T12) and the 3rd lumbar (L3) vertebrae.The position of the liver causes the right kidney to sit slightly lower than the left.Protective Layers:Each kidney is enveloped in a tough, fibrous membrane called the...
01:26Urinary Tract Infection I: Introduction
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
01:25Urinary Tract Infection II: Pathophysiology
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
01:27Acute Pyelonephritis I: Introduction
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
01:28Microbiota of the Urogenital Tract
The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...