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Updated: Jun 20, 2025

Generation and Assembly of Virus-Specific Nucleocapsids of the Respiratory Syncytial Virus
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Generation and Assembly of Virus-Specific Nucleocapsids of the Respiratory Syncytial Virus

Published on: July 27, 2021

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Structural basis for a highly conserved RNA-mediated enteroviral genome replication.

Naba Krishna Das1, Jeff Vogt1, Alisha Patel1

  • 1Department of Chemistry and Biochemistry, University of Maryland, Baltimore County, Baltimore, MD 21250, USA.

Nucleic Acids Research
|July 22, 2024
PubMed
Summary

This study reveals the conserved H-type four-way junction structure of enteroviral replication-linked RNAs (REPLRs). These structures are crucial for recruiting PCBP2, a key protein for viral genome replication and potential therapeutic targets.

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