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Wireless Magnetic Robot for Precise Hierarchical Control of Tissue Deformation.

Chao Wang¹, Zhi Zhao¹, Joonsu Han²

¹Department of Civil and Environmental Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)

|July 23, 2024

Summary

New wireless soft robots offer precise mechanotherapy for tissue repair. These magneto-active robots provide remote, programmable control for targeted tissue deformation and force application.

Keywords:

conttopology optimization ex vivo application mechanotherapy tissue deformation wireless magnetic robot with remote control

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Area of Science:

Biomedical Engineering
Robotics
Tissue Engineering

Background:

Mechanotherapy shows promise for tissue injury treatment.
Current mechanotherapy robots lack wireless control and diverse motion capabilities.

Purpose of the Study:

To develop wireless magneto-active soft robots for advanced mechanotherapy.
To enable precise, programmable tissue deformation and force application.

Main Methods:

Topology optimization and hybrid fabrication techniques were employed.
Robots were designed for hierarchical tissue-robot interaction and customized for different tissue types.
Remote magnetic actuation controlled robot deformations and force delivery.

Main Results:

Wireless magneto-active soft robots achieved programmatic deformations under remote magnetic actuation.
Robots delivered precise compressing, stretching, shearing, and multimodal forces to tissues.
Customized robots induced accurate deformations in porcine muscle, liver, and heart tissues with high durability.

Conclusions:

The developed soft robots offer a new platform for next-generation mechanotherapy.
The design framework allows for customized robots tailored to specific tissue properties.
This approach provides precise and predictable mechanical forces for tissue treatment.